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Wednesday, February 17, 2016

Kerala PSC : Pharmacist : Previous Question Paper

1. Physostigmine act as a cholmergic drug by:
(A) Directly binding with nicotimc receptors
(B) Binding with muscarinic receptors
lithibiting cholinesterase enzyme _i(D) Binding with f31 receptors
2. Which among the following is not a natural insecticide?
(A) Chrysanthemum cinerariefolium
(B) Nicotiana tobacum
(C) Ryania speciosa
(D) Piper nigrum
3. Most common adverse effect of non steroidal anti inflammatory agent:
(A) CNS toxicity (B) Castro intestinal toxicity
(C) Cardiac toxicity (D) Skin rashes
4 , pep not ii1w
(A) ronchospasm
(C) Hypersensitivity reaction
5. Barbiturate which is used for the inductiofl of anesthesia is:
(A) Phenobarbitone arbltal
(D) Thiopentone’sodium
6. A highly selective cox-2 inhibitor is:
(A) Tenoxicam (B) Ketoprofen (C) Celecoxib
7. An antiviral drug used for the treatment of Parkinsonism is:
(A) Amantadine (B) Levodopa (C) Biperiden
8. A proton pump inhibitor commonly used in the treatment of peptic ulcer
(A) Sucraif ate (B) Cimetidine
(C) Aluminium hydroxide gel (D) Omeprazole
(B) Hypertension
(D) Increased intra ocular pressure
9. Which among the following drugs is used as an emetic?
(A) Apomorphine (B) Codeine (C) Papaverine (D)
10. Antibiotic which is used as a cytotoxic agent is:
(A) Piperacillin (B) Ampicillin (C) Cloxacillin (D)
Coichicum autumnale belongs to the family:
(A) Liliaceae (B) Rutaceae (C) Moringaceae (D)
12. The act which controls the advertisement of certain drugs:
(A) The drug and Magic remedies Act 1955
(B) Insecticides Act 1968
(C) The Pharmacy Act 1948
(D) Poisons Act 1919
13. Kwashiorkor is a disease associated with the deficiency of:
(A) Vitamin B12 (B) Vitamin D (C) Carbohydrate (D)
14. Type of emulsion may be determined by:
(A) Leakage test (B) Conductivity test
(C) Toxicity test (D) Bubble point test
15. Drugs colored coated powdered or polished to conceal damage or to appear
therapeutic value than they really are is called:
(A) Spurious drug (B) Misbranded drug
(C) Adulterated drug (D) Reprocessed drug
Grease spot test is used to identify:
(A) Protein (B) Carbohydrate (C) Lipid (0)
17. Vitamin A is also called:
(A) Anti scurvitic Vitamin (B) Antisterilitic Vitamin
(C) Antihaemorrhagic Vitamin (D) Antixerophthalic Vitamin

18. The foreign bodies which are present in our body are collectively called
(A) Xenobiotics (B) Probiotics (C) Antibiotics (D)
(Jj) Primrose leaves is an adulterant of:
Datura (B) Digitalis (C) Senna (D)
20. Anthraquinone glycosides are present in:
(A) Ispaghula (B) Ephidrine (C) Aswagandha (D)
21. Physically distinct forms of same enzyme are called:
(A) Isoenzyme (B) Co-enzyme (C) Apoenzyme (D)
22. Albinism is produced due to the defect in biosynthesis of:
(A) Tyrosme (B) Melanin (C) Valine (D)
1eases a - wii,id4rug may notpurpprt oeyent oi cure is
(A) _____ -- ( ScheduleJ (D)
Which one among the following is classified as a diuretic dug?
(A) Punarnava (B) Ipecacunha (C) Cinchona (D)
25 Total energy gained from one fbi of glucose under aerobic condition is
(A) (B) 38 ATP (C) 12 ATP (D)
26. Holding temperature for moist heat sterilization is 115-118°C for:
(A) 30 minutes (B) 15 minutes (C) 0 minutes (D)
27. Chemical test for opium is done to check the presence of:
(A) Ferulic acid (B) Eugenol (C) Meconic acid (D)
28. The immunity in which the body receives readymade antibody is called:
(A) Active immunity (B) Passive immunity
(C) Natural immunity (D) Innate immunity

29. Water which is free from volatile and non - volatile impurities, micro organisms and pyro
is called
(A) Purified water (B) Potable water
(C) Water for injection (D) Sterile water for injection
30. The process in which a solid gets directly converted into vapour is called:
(A) Desiccation (B) Sublimation (C) Evaporation (D) Condensation
31. Adult dose of a drug is 240 mg calculated dose for a child of age of 12 years is:
(A) 60 mg (B) 80 mg (C) 100 mg (D) 120 mg
32. When certain drugs administered repeatedly at short intervals decreased response is obtan
is called
(A) Idiosyncrasy (B) Tolerance (C) Tachyphyláxis (D) Antagonism
33. Liquid or semi solid preparations applied with friction is called:
(A) Lotion (B) Ointment (C) Jelly (0) Liniment
34. 1 : 500 concentration of a drug means:
(A) 1 mg in 500 mL (B) 1 kg in 500 kg (C) I g in 500 mL (D) 1 g in 500 L
35. Person who wishes to manufacture of preparations containing alcohol or other narcc substance is required to obtain license from:
(A) Drugs inspector (B) Excise Commissioner
(C) Drugs Controller (D) Director of Health Services
36. The proportion of oil: water: gum in arachis oil emulsion is:
(A) 4:2:1 (B) 3:2:1 (C) 2:2:1 (D) 2:1:1
37. q.o.d. means:
(A) Four times a day (B) Every other day
(C) As needed (D) After meals
38. Superior and inferior venacava enter
(A) Right atrium (B) Left atrium (C) Right ventricle (D) Left ventricle

39. Rheumatoid arthritis is caused by:
(A) Mycobacterium tuberculosis (B) Deficiency of calcium
(C) Uric acid crystals (D) Autoimmune disorder
4O. Vasopressin is secreted by:
(A) Hypothalamus (B) Anterior pituitary
(C) Posterior pituitary (D) Adrenal medulla
41. Diabetis mellitus is caused when there is:
(A) a deficiency of insulin
(B) a deficiency of glucogan
(C) a decreased response of kidneys of vasopressin
(D) a deficiency of growth hormone
Any substance capable of triggering an immune response is called a:
(A) Heptane (B) Antibody (C) Interferon (D) Antigen
43. HIV virus destroys:
(A) T helper cells (B) Eosinophils (C) Basophils (D) Monocytes
44. Microcytic hypo chromic anemia is caused by the deficiency of:
(A) Vitamin B12 (B) Riboflavin (C) Iron (D) Folic acid
45. Otic route is used to deliver drug in to:
(A) Eye (B) Ear canal (C) Nose (D) Skin
46. Normal value of creatinine clearance:
(A) 75 - 125 mL/minute (B) 125 - 175 mL/minute
(C) 175 - 250 mL/minute (D) 259 - 275 mL/minute
47. Warfarin interacts with Phenytoin by interfering with:
(A) Absorption (B) Protein binding
(C) Metabolism (D) Elimination

48. Antidote for Iron poisoning is:
(A) Deferoxamine (B) Acetyl cystine (C) Ditnercaprol (D) Penicillamine
49. Test for water holding capacity is prescribed for:
(A) Cat gut (B) Absorbent cotton
(C) Surgical gauze (D) Sanitary Napkins
50. List of drugs to be purchased in a hospital is prepared by;
(A) Chief Pharmacist
(B) Hospital superintendent
(C) Pharmacy and therapeutic committee
(D) Drug technical advisory board
51. Safest and the most efficient method of drug distribution system is:
(A) Floor stock system (B) Complete floor stock system
(C) Charge floor stock system (D) Unit dose drug distribution system
52. Faithful adherence of the instructions given by Physician/pharmacist is called:
(A) Non compliance (B) Pharmaceutical care
(C) Patient counseling (D) Patient compliance
53. Articles published in journals are called:
(A) Primary literature (B) Secondary literature
(C) Tertiary source (D) Abstracting
54. Rate of bioavailability is greatest for:
(A) Capsule (B) Tablet (C) Suspensions (D) Solution
55. The vitamin which is given in severe cases of alcoholism is:
(A) Ascorbic acid (B) Riboflavin (C) Thiamine (D) Pyridoxine

56. Hemp is pericyclic fibers obtained from the stem of:
(A) Linum usitatissimum (B) Corchorous olitorius
(C) Cannabis sativa (D) Gossypium herbaceum
57. Basic ring present in pethidine is:
(A) Pyrrole (B) Pyridine (C) Thiophene (D) Quinoline
58. Example for a protein which is used in therapy is:
(A) Adrenaline (B) Hydrocortisone (C) Insulin (D) Thyroxin
59. Ciprofioxacm belongs to the category of:
(A) Fluoroquinolones (B) Aminoglycosides
(C) Macrolides (D) Cephalosporines
(A) Nitrogen and Oxygen (B) Sulphur and Oxygen
(C) Nitrogen Sulphur and Oxygen (D) Nitrogen and Sulphur
61. Major side effect of sodium bicarbonate when used as antacid is:
(A) Systemic alkajosis (B) Systemic acidosis
(C) Metabolic alkalosis (D) Metabolic acidosis
62. An example for antioxidant is:
(A) Sodium bisulphite (B) Sodium lauryl sulphate
(C) Sodium potassium tarfrate (D) Sodium fluoride
63. Radiopharmaceuticals should be stored in:
(A) Aluminium containers (B) Iron containers
(C) Borosilicate glass containers (D) Lead containers

64. Citric acid is added in the limit test for iron to:
(A) Provide an acidic medium
(B) To react with iron to produce a purple colour
(C) To form a complex with iron to prevent precipitation to react with acid radicals to prevent precipitation
65. Inorganic compound which is used as a dentine desensitiser is:
(A) Calcium carbonate (B) Strontium chloride
(C) Calcium chloride (13) Calcium hypochiorite
66. Gelatin is chemically:
(A) A complex carbohydrate (B) Purified wax
(C) Hydrous wool fat (13) Hydrolyzed collagenous material
67. Concentration of alcohol most effective as bactericidal is:
(A) 99% (B) 50%’ (C) 70% (13) 10%
68. Main drug used for the treatment of syphilis is:
(A) Penicillin G (B) Ampicillin (C) Gentmicin (13) Amikacn
69. Which is the second line drug for Tuberculosis?
(A) Isoniazid (B) Ciprofloxacin (C) Rifampici (D) Ethambutol
70. Saline cathartics act by:
(A) Stimulating the gastro intestinal mucosa.
(B) Increasing the gastro intestinal motility.
(C) Increasing the osmotic load of the intestinal tract.
(D) Decreasing the gastro intestinal motility.
71. Dr. Hérmann Gundert who prepared the first Dictionary in Malayalam is associated
which of the following Missions?
(A) Basel Mission (B) Missionaries of Charity
(C) English Charitable Mission . (13) Evangelical Mission
72. In which year did Sree Narayana Guru consecrate the Idol of Shiva in Aruvippuram
(A) 1912 (B) 1913 (C) 1888 (D) 1903
73. Which of the following is not a part of the preamble to the Indian Constitution?
(A) Socialism (B) Secularism (C) Federalism (D) Republic
74. Who among the foUowing wrote the work ‘Athmanuthapam’?
(A) Vagbhadananda (B) Saint Elias Kuriakose Chaavara
(C) Sree Narayana Guru (D) Chattambi Swamikal
75. In which year was the Cochin State Prajamandal formed?
(A) 6 January 1936 (B) 16 January 1941
(C) 12 August 1945 (D) 8 July 1946
\) Th of Supreme Court of India to decide the dispute between the Centre and States falls under it’s __________ Jurisdiction.
(A) Advisory (B) Appellate (C) Writ (D) Original
77. Who suggested the name ‘Al ention Movement’ for the same?
H -
(A) LC. Chacko (B) C Kesavan
(C) T.M. Varghese (D) N.y. Joseph
78. Who among the following translated Tagore’s ‘Gitanjali’- for the first time into Malayalam?
(A) Kumaranasan (B) G. Sankara Kurup -
(C) Vallathol (D) S.K. Pottakkad
79. Pick out from the following, the prominent woman leader from Malabar who participated in
the Freedom Struggle?
(A) Akkamma Cherian (B) Anna Chandi
(C) A.V. Kuttimalu Aminá (t) Thottakkad Madhavi Amma
80. The novelist to have won the ‘jrianpith Award’ for the first time from Kerala is _________
(A) G. Sanakara Kurup (B) Thakazhi
(C) S.K. Pottakkad (D) M.T. Vasudevan Nair
81. The members of the State Public Service Commission are appointed by:
(A) Chief Minister (B) Chief Justice
(C) Chief Secretary (D) Governor
82. Who among the following was the Chairman of the Guruvayoor Satyagraha Committee?
(A) K. Kelappan (B) A.K. Gopalan
(C) C. Krishnan (D) Mannathu Padmanabhan
83. Who was the first Vice-Chancellor of Kerala University?
(A) Sardar K.M. Panicker (B) Joseph Mundasseri
(C) John Mathai (D) M.V. Paili
Where is the BRICS Bank being established?
(A) China (B) India (C) Brazil (D) South Africa
85. On which date was the National Food Security Act signed into Law?
(A) 13 September 2013 (B) 12 September 2013
(C) 26 August 2013 (D) 3 August 2013
86. Who among the following is the present Chairman of The National Women’s Commission?
(A) Mano Sharma (B) Sujatha Singh
(C) Lalitha Kumaramangalam (D) Jayanthy Patnaik
87. Who was the founder of ‘Samatwa Samajam’ ?
(A) Ayyankali (B) Chattambi Swamikal
(C) Swami Agamananda (D) Ayya Vaikundar

88. Who among the following Keralites, was the Editor of the Newspaper, ‘The Madras
Standard’ ?
(A) G.P. Pillai (B) K.P. Kesava Menon
(C) Kumaranasan (D) C.V. Kunjuraman
Which Article of the Indian Constitution is related to Presidential Rule in States?
(A) Article 352 (B) Article 356 (C) Article 359 (D) Article 360
90. Who is popularly known as the ‘Lincoln of Kerala’?
(A) K. Kelappan (B) Velukkutty Arayan
(C) A.K. Gopalan (D) Pandit K.P. Karuppan
91. The cathartic property of castor oil is due to the p1esence of:
(A) Linoleic acid (B) Arachidonic acid
(C) Ricinoleic acid (D) Stearic acid
92. d-Tubocurarine is a:
(A) Neuromuscular blocking agent
(B) Anticholme esterase
(C) Anaesthetic
(D) Neuro degenerative agent
93. The schedule which provide standard for ophthalmic preparation:
(A) Schedule P (B) Schedule R (C) Schedule FF (D) Schedule Y
94. Cifric acid cycle takes place in:
(A) Liver (B) Mitochondria
(C) Endoplasmic reticulum (D) Nucleic acid
95. The pyrimidine component of RNA is:
(A) Adenine (B) Guanine (C) Thymine (D) Uracil

96. Major side effect of chioramphenicol is:
(A) Bone marrow depression (B) GIT disturbances
(C) Insomnia (D) Profound dyspnea
97. Example for a five membered hetrocyclic compound with one hetro atom is:
(A) Pyrimidine (B) Furane (C) Aziridine (D) Phenanthrene
98. One table spoon full is:
(A) 4 mL (B) 6 mL (C) 8 mL (D) 15
99. Bence Jones Proteins found in urine occur in:
(A) Liver diseases (B) Diabetes mellitus
(C) Multiple myeloma (D) Thalassemia
100. Preparations of digitalis is used in the treatment of:
(A) Hypertension (B) Gout
(C) Myocardial infarction (D) Congestive cardiac failure

200/2015 6

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